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Structure of 280-13-7
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8-Oxa-3-azabicyclo[3.2.1]octane features a rigid, polar heterocyclic framework that integrates an oxygen atom and a nitrogen heteroatom within a strained bicyclic scaffold. This configuration imparts enhanced solubility and conformational control, enabling efficient incorporation into bioactive molecules. The scaffold serves as a stable, metabolically resilient core in medicinal chemistry applications.
8-Oxa-3-azabicyclo[3.2.1]octane serves as a rigid, bicyclic scaffold with defined stereochemistry, enabling precise spatial orientation of functional groups in medicinal chemistry applications. The molecule features an oxygen atom at the bridgehead and a nitrogen within the ring system, providing a polar, hydrogen-bond-capable site for molecular recognition. Its bench-stable structure facilitates straightforward derivatization, supports orthogonal functional group handling, and functions effectively in standard coupling and reduction protocols. This scaffold is particularly valuable for constructing bioactive heterocycles and modulating pharmacokinetic properties in lead optimization.
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GHS Pictogram :
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GHS No : GHS02,GHS07
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Signal Word : Danger
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UN#: 1993
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H226-H315-H319-H335
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Precautionary Statements : P261-P305+P351+P338
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Lot numbers can be found on the outside label of a product: