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Structure of 2820-37-3
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3,4-Dimethyl-1H-pyrazole is a bench-stable, electron-rich heterocycle featuring two methyl groups at the 3 and 4 positions, enhancing its lipophilicity and metabolic stability. This structural motif enables efficient integration into bioactive scaffolds, particularly in medicinal chemistry applications requiring moderate polarity and enhanced membrane permeability.
3,4-Dimethyl-1H-pyrazole serves as a versatile heterocyclic building block in medicinal chemistry and agrochemical synthesis. Its stability under standard reaction conditions enables reliable incorporation into complex molecules. The methyl substituents enhance lipophilicity and metabolic stability, while the pyrazole core facilitates hydrogen bonding and π–stacking interactions. This compound functions effectively as a bioisostere for phenyl rings or amides, enabling improved solubility and target engagement in lead optimization campaigns.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H318-H412
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Precautionary Statements : P264-P270-P273-P280-P330-P501
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Lot numbers can be found on the outside label of a product: