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Structure of 284462-37-9
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4-(4-Aminophenoxy)-N-methylpicolinamide features a polar aniline ether linkage paired with a sterically hindered N-methylpyridine amide, enabling robust solubility in aqueous and organic media. This scaffold integrates electron-rich aromatic systems with directional hydrogen-bonding capacity, facilitating precise molecular recognition in drug discovery applications.
4-(4-Aminophenoxy)-N-methylpicolinamide serves as a versatile building block for medicinal chemistry, enabling the construction of bioactive heterocycles through standard amide coupling and electrophilic substitution reactions. The aniline moiety supports facile derivatization, while the picolinamide framework enhances solubility and facilitates metal coordination in catalytic systems. Bench-stable and readily purified by recrystallization, it functions effectively in multi-step syntheses targeting pharmaceutical scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: