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Structure of 28547-13-9
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This methylsulfonamido-substituted benzoic acid integrates a polar sulfonamide group with a carboxylic acid functionality, enabling versatile conjugation and solubility enhancement in medicinal chemistry applications. The para-positioned sulfonamide imparts strong hydrogen-bonding capacity, while the acid moiety facilitates derivatization under standard coupling conditions.
3-(Methylsulfonamido)benzoic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles and pharmaceutical scaffolds. Its orthogonal functional groups—carboxylic acid and methylsulfonamide—facilitate diverse coupling reactions, including amide bond formation and Suzuki-Miyaura cross-coupling. The molecule exhibits good bench stability, solubility in common organic solvents, and compatibility with standard purification methods, making it well-suited for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501
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Lot numbers can be found on the outside label of a product: