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Structure of 286371-49-1
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7-(Benzyloxy)-4-chloro-6-methoxyquinoline features a benzyl ether at the 7-position and a chloro substituent at the 4-position, enhancing electron deficiency for targeted coupling reactions. The methoxy group at the 6-position improves solubility and stability under standard conditions, enabling efficient integration into complex heterocyclic architectures.
7-(Benzyloxy)-4-chloro-6-methoxyquinoline serves as a versatile building block for medicinal chemistry and heterocyclic synthesis, enabling efficient functionalization at the C4 position via palladium-catalyzed cross-coupling. The benzyloxy group offers orthogonal protection and can be readily removed under mild conditions, while the methoxy and chloro substituents provide predictable reactivity in electrophilic substitution and transition-metal-mediated transformations. Its bench-stable nature and compatibility with standard synthetic workflows make it ideal for scaffold diversification in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: