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CS-W001157 4
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(S)-11-Benzyl-1-(9H-fluoren-9-yl)-3,6,9,12,15-pentaoxo-2-oxa-4,7,10,13,16-pentaazaoctadecan-18-oic acid

  • CAS No. 2866302-04-5

  • Cat. No. CS-0616149
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S)-11-Benzyl-1-(9H-fluoren-9-yl)-3,6,9,12,15-pentaoxo-2-oxa-4,7,10,13,16-pentaazaoctadecan-18-oic acid|CS-0616149

Structure of 2866302-04-5

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General Information

  • CAS No. 2866302-04-5
  • Cat. No. CS-0616149
  • Purity ≥95%
  • MDL No. None
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃₂H₃₃N₅O₈
  • Molecular Weight 615.63
  • Synonym(s) None
  • SMILES O=C(NCC(N[C@@H](CC1=CC=CC=C1)C(NCC(NCC(O)=O)=O)=O)=O)CNC(OCC2C3=C(C=CC=C3)C4=C2C=CC=C4)=O

Description

(S)-11-Benzyl-1-(9H-fluoren-9-yl)-3,6,9,12,15-pentaoxo-2-oxa-4,7,10,13,16-pentaazaoctadecan-18-oic acid features a rigid fluorenyl scaffold paired with a benzylated side chain, enabling precise spatial control in peptide conjugation. The extended polyamide backbone incorporates multiple carbonyl and amine functionalities, facilitating efficient coupling reactions under standard conditions. This design delivers high solubility and stability during solid-phase synthesis workflows.

Application

(S)-11-Benzyl-1-(9H-fluoren-9-yl)-3,6,9,12,15-pentaoxo-2-oxa-4,7,10,13,16-pentaazaoctadecan-18-oic acid serves as a versatile, bench-stable building block for the synthesis of complex peptide-like scaffolds and macrocyclic architectures. Its orthogonal functional groups enable selective derivatization in multi-step syntheses, while the fluorenyl moiety facilitates purification via chromatography. The molecule functions effectively in solid-phase and solution-phase coupling protocols, offering high compatibility with standard amine-reactive reagents.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   192.03
  • LogP   0.6858
  • H_Acceptors   7
  • H_Donors   6
  • Rotatable_Bonds   14

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