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Structure of 1036027-54-9
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5-(Trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine delivers a potent electron-deficient heterocyclic scaffold ideal for medicinal chemistry. The trifluoromethyl group enhances metabolic stability and membrane permeability, while the fused pyrrolopyridine core enables robust coupling in cross-coupling reactions. This compound serves as a key building block in targeted kinase inhibitors and CNS drug discovery programs.
5-(Trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to bioactive scaffolds. Its trifluoromethyl group enhances metabolic stability and modulates lipophilicity, while the fused pyrrolopyridine core supports diverse functionalization via palladium-catalyzed coupling reactions. The compound exhibits excellent bench stability and compatibility with standard synthetic protocols, facilitating incorporation into complex molecular architectures.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: