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Structure of 287193-01-5
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tert-Butyl 3-ethynylazetidine-1-carboxylate is a bench-stable, moisture-tolerant building block featuring a reactive alkyne handle and strained azetidine core. This combination enables efficient copper-catalyzed click chemistry and facilitates the incorporation of nitrogen-rich heterocycles into bioactive molecules with minimal steric interference.
tert-Butyl 3-ethynylazetidine-1-carboxylate serves as a versatile building block for constructing nitrogen-containing heterocycles, enabling efficient access to azetidinyl scaffolds via copper-catalyzed cycloadditions and Sonogashira couplings. The terminal alkyne functionality exhibits high compatibility with palladium- and copper-mediated transformations, while the tert-butoxycarbonyl group provides robust protection for amine intermediates, facilitating purification and stability during multistep syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: