2H-1,2,3-Triazole

Name: 2H-1,2,3-Triazole
Brand: ChemScene
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CAS No. 288-35-7
Cat. No. CS-0145707
Purity≥98%
MDL No.MFCD00962232

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 288-35-7

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Description

2H-1,2,3-Triazole is a stable, heterocyclic nitrogen-rich compound featuring a fused five-membered ring with three nitrogen atoms. This electron-deficient structure enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC), serving as a key scaffold in bioconjugation and medicinal chemistry. Its bench-stable nature facilitates reliable use in diverse synthetic workflows.

Application

2H-1,2,3-Triazole serves as a stable, bench-ready heterocyclic building block for click chemistry and medicinal chemistry applications. Its regioselective reactivity enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC), facilitating rapid access to triazole-linked conjugates. The functional group tolerance and metabolic stability of the triazole ring make it a valuable scaffold in drug discovery and materials science.

General Information

CAS No. 288-35-7
Cat. No. CS-0145707
Purity ≥98%
MDL No. MFCD00962232
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂H₃N₃
Molecular Weight 69.07
Synonym(s) 1H-1,2,3-Triazole
SMILES N1=CC=NN1

Computational Chemistry Data

TPSA 41.57
LogP -0.1953
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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2H-1,2,3-Triazole

CAS No. 288-35-7

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