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Structure of 3697-70-9
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5-Azaspiro[2.4]heptan-4-one is a rigid, nitrogen-containing spirocyclic ketone featuring a fused bicyclic architecture that imparts conformational stability. This scaffold integrates a pyrrolidinone core with defined stereochemical control, enabling its use in medicinal chemistry for probing bioactive conformations and constructing complex heterocycles.
5-Azaspiro[2.4]heptan-4-one serves as a rigid, bicyclic scaffold for medicinal chemistry applications, offering enhanced metabolic stability and defined spatial orientation. Its ketone functionality enables direct derivatization via nucleophilic addition or reductive amination, while the adjacent nitrogen supports salt formation and hydrogen bonding interactions. The spirocyclic core exhibits excellent bench stability and facilitates efficient purification, making it a practical building block for targeted library synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: