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Structure of 2902-65-0
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2-Iodo-isophthalic acid is a bench-stable, moisture-tolerant diacid featuring a para-substituted aromatic core with a strategically positioned iodine atom. This configuration enables direct functionalization via palladium-catalyzed cross-coupling reactions, facilitating the synthesis of complex arylated scaffolds in medicinal chemistry and materials science applications.
2-Iodo-isophthalic acid serves as a versatile building block for palladium-catalyzed cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl scaffolds. Its ortho-iodo functionality exhibits high reactivity in Suzuki, Stille, and Negishi couplings, while the carboxylic acid groups provide handles for derivatization or metal coordination. The compound demonstrates excellent bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis in medicinal chemistry and materials development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: