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CS-W001157 4
Total: USD 88.00

6-Phenylnicotinic acid

  • CAS No. 29051-44-3

  • Cat. No. CS-0145812
  • Purity≥98%
  • MDL No.MFCD03086128
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

6-Phenylnicotinic acid|CS-0145812

Structure of 29051-44-3

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Description

6-Phenylnicotinic acid is a functionalized nicotinic acid derivative featuring a phenyl group at the 6-position, enabling direct integration into bioactive scaffolds. This aryl-substituted pyridine carboxylic acid offers enhanced π-stacking potential and metabolic stability, facilitating its use in medicinal chemistry campaigns targeting receptor modulators and kinase inhibitors under standard bench conditions.

Application

6-Phenylnicotinic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical scaffolds. Its ortho-substituted pyridine core offers enhanced metabolic stability and favorable binding interactions. The carboxylic acid functionality facilitates direct derivatization or coupling reactions, while the phenyl group provides structural rigidity and π-stacking potential. This compound exhibits excellent bench stability and compatibility with standard synthetic protocols, making it well-suited for iterative library construction and process-scale applications.

General Information

  • CAS No. 29051-44-3
  • Cat. No. CS-0145812
  • Purity ≥98%
  • MDL No. MFCD03086128
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₉NO₂
  • Molecular Weight 199.21
  • Synonym(s) None
  • SMILES O=C(C1=CC=C(C2=CC=CC=C2)N=C1)O

Computational Chemistry Data

  • TPSA   50.19
  • LogP   2.4468
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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