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Structure of 29051-44-3
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6-Phenylnicotinic acid is a functionalized nicotinic acid derivative featuring a phenyl group at the 6-position, enabling direct integration into bioactive scaffolds. This aryl-substituted pyridine carboxylic acid offers enhanced π-stacking potential and metabolic stability, facilitating its use in medicinal chemistry campaigns targeting receptor modulators and kinase inhibitors under standard bench conditions.
6-Phenylnicotinic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical scaffolds. Its ortho-substituted pyridine core offers enhanced metabolic stability and favorable binding interactions. The carboxylic acid functionality facilitates direct derivatization or coupling reactions, while the phenyl group provides structural rigidity and π-stacking potential. This compound exhibits excellent bench stability and compatibility with standard synthetic protocols, making it well-suited for iterative library construction and process-scale applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: