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CS-W001157 4
Total: USD 88.00

6-Bromonicotinic acid

  • CAS No. 6311-35-9

  • Cat. No. CS-W002864
  • Purity≥98%
  • MDL No.MFCD01927100

*For research and further manufacturing use only, not for direct human use.

6-Bromonicotinic acid|CS-W002864

Structure of 6311-35-9

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General Information

  • CAS No. 6311-35-9
  • Cat. No. CS-W002864
  • Purity ≥98%
  • MDL No. MFCD01927100
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄BrNO₂
  • Molecular Weight 202.01
  • Synonym(s) None
  • SMILES BrC1=NC=C(C(O)=O)C=C1

Description

6-Bromonicotinic acid features a bromine substituent at the pyridine ring's 6-position, enabling direct functionalization in cross-coupling reactions. This bench-stable derivative serves as a key building block for bioactive heterocycles and pharmaceutical intermediates, offering enhanced reactivity compared to its unsubstituted analog.

Synthesis

  • Route1

    References

    • Oyston, Stephen; Wang, Changsheng; Perepichka, Igor F.; Batsanov, Andrei S.; Bryce, Martin R.; Ahn, Jin H.; Petty, Michael C. Journal of Materials Chemistry, 2005 , vol. 15, # 48 p. 5164 - 5173
  • Route2
    • 6-Hydroxynicotinic acid Avatrombopag Impurity|CS-0377520
      5006-66-6
    • ~%
    • In-stock
      6-Bromonicotinic acid|CS-W002864
      6311-35-9

    References

    • US4112102 A1, ;
  • Route3

    References

    • Synthesis, , # 1 p. 87 - 92

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Computational Chemistry Data

  • TPSA   50.19
  • LogP   1.5423
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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