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Structure of 2918294-00-3
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3-Fluoro-4-methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile integrates a boronate handle with electron-withdrawing nitrile and polar methoxy groups, enabling efficient Suzuki-Miyaura coupling under standard conditions. This bench-stable reagent facilitates the construction of complex aryl architectures in medicinal chemistry and materials synthesis.
3-Fluoro-4-methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile serves as a versatile boronate building block in palladium-catalyzed cross-coupling reactions. Its ortho-fluoro and methoxy substituents enable predictable regioselective functionalization, while the pinacol boronate group offers excellent bench stability, ease of handling, and compatibility with diverse reaction conditions. Functions effectively in Suzuki-Miyaura couplings to construct biaryl and heteroaryl scaffolds common in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: