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Structure of 29241-66-5
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5-Bromo-2-fluoronicotinic acid features a strategically positioned bromine and fluorine substituent on the pyridine ring, enabling direct incorporation into Suzuki-Miyaura cross-coupling and other transition-metal-catalyzed transformations. The electron-deficient heterocycle facilitates efficient functionalization in medicinal chemistry and materials synthesis workflows under standard conditions.
5-Bromo-2-fluoronicotinic acid serves as a versatile building block for the synthesis of biologically active heterocycles and pharmaceutical intermediates. Its dual halogenation enables efficient palladium-catalyzed cross-coupling reactions, while the carboxylic acid functionality supports direct derivatization or activation for amide formation. The compound exhibits excellent bench stability and facilitates orthogonal functional group manipulation in complex molecule assembly.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: