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Structure of 294860-58-5
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Methyl 2-(5-bromo-2-methoxyphenyl)acetate features a brominated aromatic core with a methoxy substituent and a pendant ester-functionalized side chain. This combination imparts enhanced stability and solubility in polar organic solvents, enabling efficient integration into Suzuki-Miyaura coupling sequences and other transition-metal-catalyzed transformations. The molecule’s electron-deficient aryl ring facilitates selective functionalization, while the methyl ester group serves as a versatile handle for downstream derivatization under mild conditions.
Methyl 2-(5-bromo-2-methoxyphenyl)acetate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to biaryl and heterocyclic scaffolds via palladium-catalyzed cross-coupling reactions. The bromo group facilitates Suzuki, Stille, and Negishi couplings, while the methoxy and ester functionalities provide orthogonal reactivity and structural stability. Its bench-stable nature and compatibility with standard reaction conditions make it well-suited for medicinal chemistry and process development workflows.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: