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CS-W001157 4
Total: USD 88.00

2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)malonic acid

  • CAS No. 296261-32-0

  • Cat. No. CS-0149811
  • Purity≥97%
  • MDL No.MFCD09841915

*For research and further manufacturing use only, not for direct human use.

2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)malonic acid|CS-0149811

Structure of 296261-32-0

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General Information

  • CAS No. 296261-32-0
  • Cat. No. CS-0149811
  • Purity ≥97%
  • MDL No. MFCD09841915
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₈H₁₅NO₆
  • Molecular Weight 341.31
  • Synonym(s) FMoc-AMinoMalonic acid FMoc-AMinoMalonic acid
  • SMILES O=C(O)C(C(O)=O)NC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O

Description

This fluorenylmethoxycarbonyl-protected amino malonic acid derivative serves as a key intermediate in peptide synthesis, offering enhanced solubility and stability under standard conditions. The Fmoc group enables efficient orthogonal protection, while the malonic acid backbone facilitates subsequent functionalization in multistep sequences.

Application

2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)malonic acid serves as a robust, bench-stable amino acid equivalent for peptide synthesis, enabling efficient Nα-protecting group installation via carbodiimide-mediated coupling. Its fluorenylmethoxycarbonyl (Fmoc) moiety provides orthogonal deprotection under mild basic conditions, while the malonic acid core supports versatile derivatization and integration into heterocyclic scaffolds. Ideal for solid-phase and solution-phase workflows, it offers high functional group tolerance and clean purification profiles.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   112.93
  • LogP   2.0629
  • H_Acceptors   4
  • H_Donors   3
  • Rotatable_Bonds   5

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