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Structure of 29682-15-3
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Methyl 5-bromopyridine-2-carboxylate features a brominated pyridine core with a methyl ester at the ortho position, enabling selective functionalization in cross-coupling reactions. The electron-deficient heterocycle enhances reactivity in palladium-catalyzed transformations, while the ester group provides a handle for further derivatization. This bench-stable reagent supports efficient access to complex nitrogen-containing scaffolds in medicinal chemistry and materials science.
Methyl 5-bromopyridine-2-carboxylate serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its well-defined bromo and ester functionalities. The pyridine core provides orthogonal reactivity, while the methyl ester facilitates downstream transformations such as hydrolysis or amidation. Its bench stability and compatibility with standard synthetic protocols make it a reliable intermediate for constructing complex heterocyclic scaffolds and API candidates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: