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2-Deoxy-2-fluoro-D-glucose

  • CAS No. 29702-43-0

  • Cat. No. CS-0182797
  • Purity≥98%
  • MDL No.MFCD00077527

*For research and further manufacturing use only, not for direct human use.

2-Deoxy-2-fluoro-D-glucose|CS-0182797

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General Information

  • CAS No. 29702-43-0
  • Cat. No. CS-0182797
  • Purity ≥98%
  • MDL No. MFCD00077527
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₁FO₅
  • Molecular Weight 182.15
  • Synonym(s) 2-Fluoro-2-deoxy-D-glucose; 2-Deoxy-2-fluoro-D-glucopyranose; Fluorodeoxyglucose
  • SMILES OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](F)C=O

Description

Uptake by brain and heart tissues proceeds rapidly via glucose transporters, yet 2-Fluoro-2-deoxy-D-glucose (CAS 29702-43-0) resists glycolytic phosphorylation, accumulating intracellularly to disrupt metabolic flux without inducing cytotoxicity.

Application

2-Fluoro-2-deoxy-D-glucose (CAS 29702-43-0) drives metabolic pathway analysis by mimicking glucose uptake while resisting further breakdown. It accumulates in cells with high glycolytic activity. Researchers use it to map glycolytic flux, study the Warburg effect in tumors, and track brain metabolism in real time.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P332+P317-P337+P317-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   97.99
  • LogP   -2.4016
  • H_Acceptors   5
  • H_Donors   4
  • Rotatable_Bonds   5

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