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Structure of 2973-50-4
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2-(2-Aminophenyl)acetonitrile features a benzene ring bearing both an ortho-aminomethyl and nitrile group, enabling direct integration into transition-metal-catalyzed coupling reactions. The amine functionality facilitates derivatization, while the nitrile group offers high stability under standard bench conditions. This scaffold supports rapid access to complex heterocycles in medicinal chemistry and materials synthesis.
2-(2-Aminophenyl)acetonitrile serves as a versatile building block in medicinal chemistry, enabling direct access to substituted quinoline and benzodiazepine scaffolds via cyclization reactions. Its ortho-amino and nitrile functionalities offer complementary reactivity for palladium-catalyzed coupling, electrophilic substitution, and condensation processes. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis campaigns in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: