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Structure of 29886-62-2
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4-(Thiophen-2-yl)benzoic acid features a rigid, planar architecture integrating a thiophene ring with a benzoic acid moiety. This arrangement enhances π-conjugation and facilitates crystal packing, enabling efficient solid-state reactivity. The carboxylic acid group provides a robust handle for derivatization via esterification, amidation, or metal coordination. Its moisture-tolerant nature supports handling under standard bench conditions.
4-(Thiophen-2-yl)benzoic acid serves as a versatile building block for constructing biaryl-thiophene scaffolds prevalent in pharmaceutical and materials chemistry. Its carboxylic acid functionality enables direct amidation, esterification, or coupling reactions under standard conditions. The molecule exhibits good bench stability, moderate solubility in organic solvents, and tolerance to common functional groups, facilitating straightforward purification and integration into multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: