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CS-W001157 4
Total: USD 88.00

2,5-Difluorobenzoic acid

  • CAS No. 2991-28-8

  • Cat. No. CS-W020593
  • Purity≥97%
  • MDL No.MFCD00002410

*For research and further manufacturing use only, not for direct human use.

2,5-Difluorobenzoic acid|CS-W020593

Structure of 2991-28-8

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General Information

  • CAS No. 2991-28-8
  • Cat. No. CS-W020593
  • Purity ≥97%
  • MDL No. MFCD00002410
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄F₂O₂
  • Molecular Weight 158.10
  • Synonym(s) NSC 190310; Benzoic acid, 2,5-difluoro-
  • SMILES O=C(O)C1=CC(F)=CC=C1F

Description

2,5-Difluorobenzoic acid features a rigid aromatic core with two fluorine atoms positioned at the 2 and 5 ring sites, imparting enhanced electron-withdrawing character and improved metabolic stability. This configuration supports efficient coupling reactions in medicinal chemistry and enables precise tuning of solubility and lipophilicity in drug discovery applications.

Synthesis

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    • In-stock
      2,5-Difluorobenzoic acid|CS-W020593
      2991-28-8

    References

    • Journal of Physical Chemistry A, , vol. 104, # 2 p. 352 - 361
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    • In-stock
      2,5-Difluorobenzoic acid|CS-W020593
      2991-28-8

    References

    • Journal of Physical Chemistry A, , vol. 104, # 2 p. 352 - 361
  • Route3

    References

    • Journal of Physical Chemistry A, , vol. 104, # 2 p. 352 - 361

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   1.663
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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