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CS-W001157 4
Total: USD 88.00

Methyl 4-amino-3-hydroxybenzenecarboxylate

  • CAS No. 63435-16-5

  • Cat. No. CS-W000706
  • Purity≥95%
  • MDL No.MFCD00017093
  • HazMat Fee +

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    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

Methyl 4-amino-3-hydroxybenzenecarboxylate|CS-W000706

Structure of 63435-16-5

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Description

Methyl 4-amino-3-hydroxybenzenecarboxylate features a strategically positioned amino group and a phenolic hydroxyl, enabling dual functionalization in synthetic sequences. The methyl ester provides stability and facilitates downstream transformations. This ortho-substituted scaffold offers enhanced solubility and reactivity under standard conditions, supporting efficient incorporation into complex molecular architectures.

Application

Methyl 4-amino-3-hydroxybenzenecarboxylate serves as a versatile building block in synthetic organic chemistry, enabling the construction of bioactive heterocycles and pharmaceutical intermediates. The molecule combines ortho-directed reactivity from the amino and hydroxyl groups with the electrophilic handle of the ester, facilitating regioselective functionalization. Its bench-stable nature and compatibility with standard coupling and cyclization protocols make it suitable for iterative synthesis workflows in medicinal chemistry and process development.

General Information

  • CAS No. 63435-16-5
  • Cat. No. CS-W000706
  • Purity ≥95%
  • MDL No. MFCD00017093
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉NO₃
  • Molecular Weight 167.16
  • Synonym(s) Methyl 4-amino-3-hydroxybenzoate
  • SMILES O=C(OC)C1=CC=C(N)C(O)=C1

Computational Chemistry Data

  • TPSA   72.55
  • LogP   0.761
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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