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Structure of 29958-12-1
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6-Iodopyridin-3-amine delivers a reactive iodine handle at the 6-position, enabling facile cross-coupling in palladium-catalyzed transformations. The pyridin-3-amine core provides a strong nitrogen donor for metal coordination and enhances solubility in polar solvents. This combination supports efficient synthesis of functionalized heterocycles under standard conditions.
6-Iodopyridin-3-amine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions for the construction of biaryl and heteroaryl scaffolds. The iodide group facilitates efficient Suzuki, Stille, and Negishi couplings, while the pyridin-3-amine functionality provides a handle for further derivatization via amide formation or metal complexation. Its bench-stable crystalline form simplifies handling and purification, making it well-suited for iterative synthesis campaigns in drug discovery and process development.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H312-H315-H317-H318-H319-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P272-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: