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CS-W001157 4
Total: USD 88.00

CL-59089

  • CAS No. 3008-61-5

  • Cat. No. CS-0072874
  • Molecule weight199.27
  • Purity≥98%
  • MDL No.MFCD06340096

*For research and further manufacturing use only, not for direct human use.

CL-59089|CS-0072874

Structure of 3008-61-5

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General Information

  • CAS No. 3008-61-5
  • Cat. No. CS-0072874
  • Purity ≥98%
  • MDL No. MFCD06340096
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₃N₃OS
  • Molecular Weight 199.27
  • Synonym(s) 4-(Morpholin-4-ylmethyl)-1,3-thiazol-2-amine
  • SMILES NC1=NC(CN2CCOCC2)=CS1

Description

CL-59089 is a bench-stable, electron-deficient heterocycle featuring a fused pyridine core with strategically positioned nitro and cyano substituents. This compound integrates readily into cross-coupling workflows and serves as a key scaffold for synthesizing bioactive analogs in medicinal chemistry.

Application

CL-59089 serves as a robust building block for heterocyclic scaffolds, enabling efficient construction of nitrogen-containing ring systems via standard cyclization protocols. Its functional group tolerance and bench stability facilitate reliable use in multi-step syntheses, particularly in medicinal chemistry workflows requiring predictable reactivity and straightforward purification.

Synthesis

  • Route1
    • null|null
      1193104-30-1
    • ~%
    • In-stock
      CL-59089|CS-0072874
      3008-61-5

    References

    • SIRTRIS PHARMACEUTICALS, INC.; VU, Chi, B. Patent: WO2010/19606 A1, 2010 ; Location in patent: Page/Page column 80-81 ; WO 2010/019606 A1
  • Route2
    • null|null
      110-91-8
    • In-stock
      4-(Chloromethyl)thiazol-2-amine hydrochloride|CS-W019518
      59608-97-8
    • ~%
    • In-stock
      CL-59089|CS-0072874
      3008-61-5

    References

    • BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO. KG Patent: WO2008/86047 A1, 2008 ; Location in patent: Page/Page column 153-154 ; WO 2008/086047 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   51.38
  • LogP   0.5575
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   2

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