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Structure of 301673-14-3
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tert-Butyl 4-iodopiperidine-1-carboxylate features a bench-stable, moisture-tolerant piperidine scaffold bearing a reactive iodide handle at the 4-position. This versatile intermediate enables direct coupling in cross-coupling reactions, facilitating rapid access to functionalized piperidine derivatives used in medicinal chemistry and target-oriented synthesis.
tert-Butyl 4-iodopiperidine-1-carboxylate serves as a versatile building block in medicinal chemistry, enabling efficient late-stage functionalization via Pd-catalyzed cross-coupling reactions. The iodide group facilitates reliable C–C and C–heteroatom bond formation under standard conditions, while the tert-butyl carbamate protects the piperidine nitrogen with excellent bench stability and ease of removal. Its compatibility with diverse reaction partners makes it a practical choice for constructing complex heterocyclic scaffolds and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: