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CS-W001157 4
Total: USD 88.00

Dicyclohexyl(2,4,6-triisopropylphenyl)phosphine

  • CAS No. 303111-96-8

  • Cat. No. CS-W011704
  • Purity≥97%
  • MDL No.MFCD11656073

*For research and further manufacturing use only, not for direct human use.

Dicyclohexyl(2,4,6-triisopropylphenyl)phosphine|CS-W011704

Structure of 303111-96-8

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General Information

  • CAS No. 303111-96-8
  • Cat. No. CS-W011704
  • Purity ≥97%
  • MDL No. MFCD11656073
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₇H₄₅P
  • Molecular Weight 400.63
  • Synonym(s) (2,4,6-Tri-isopropyl)phenyl)di-cyclohexylphosphine
  • SMILES CC(C1=C(P(C2CCCCC2)C3CCCCC3)C(C(C)C)=CC(C(C)C)=C1)C

Application

Dicyclohexyl(2,4,6-triisopropylphenyl)phosphine serves as a sterically hindered, bench-stable phosphine ligand that enables efficient cross-coupling reactions under mild conditions. Its enhanced electronic and steric profile facilitates catalyst activation in palladium-catalyzed transformations, particularly effective in Suzuki-Miyaura and Negishi couplings. The ligand exhibits high functional group tolerance and improves reaction reproducibility with sensitive substrates, making it a practical choice for complex molecule synthesis and process-scale applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   0
  • LogP   8.8294
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   6

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