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Structure of 303752-38-7
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This bicyclic amino acid derivative features a tert-butoxycarbonyl-protected amine and a carboxylic acid group on the rigid [1.1.1]bicycloalkane scaffold, enabling stable incorporation into peptide architectures. The steric congestion enhances conformational control in synthetic sequences.
3-((tert-Butoxycarbonyl)amino)bicyclo[1.1.1]pentane-1-carboxylic acid serves as a robust, bench-stable building block for constructing constrained peptidomimetics and bioactive scaffolds. The tert-butyl carbamate (Boc) group enables straightforward protection and deprotection under mild acidic conditions, while the rigid bicyclo[1.1.1]pentane core imparts exceptional conformational stability and metabolic resistance. This compound facilitates efficient amide coupling and functionalization in solid-phase and solution-phase synthesis, offering high compatibility with diverse reaction conditions and enabling rapid access to complex molecular architectures.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P260-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: