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CS-W001157 4
Total: USD 88.00

3-((tert-Butoxycarbonyl)amino)bicyclo[1.1.1]pentane-1-carboxylic acid

  • CAS No. 303752-38-7

  • Cat. No. CS-W000155
  • Purity≥97%
  • MDL No.MFCD09971715
  • HazMat Fee +

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    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3-((tert-Butoxycarbonyl)amino)bicyclo[1.1.1]pentane-1-carboxylic acid|CS-W000155

Structure of 303752-38-7

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Description

This bicyclic amino acid derivative features a tert-butoxycarbonyl-protected amine and a carboxylic acid group on the rigid [1.1.1]bicycloalkane scaffold, enabling stable incorporation into peptide architectures. The steric congestion enhances conformational control in synthetic sequences.

Application

3-((tert-Butoxycarbonyl)amino)bicyclo[1.1.1]pentane-1-carboxylic acid serves as a robust, bench-stable building block for constructing constrained peptidomimetics and bioactive scaffolds. The tert-butyl carbamate (Boc) group enables straightforward protection and deprotection under mild acidic conditions, while the rigid bicyclo[1.1.1]pentane core imparts exceptional conformational stability and metabolic resistance. This compound facilitates efficient amide coupling and functionalization in solid-phase and solution-phase synthesis, offering high compatibility with diverse reaction conditions and enabling rapid access to complex molecular architectures.

General Information

  • CAS No. 303752-38-7
  • Cat. No. CS-W000155
  • Purity ≥97%
  • MDL No. MFCD09971715
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₇NO₄
  • Molecular Weight 227.26
  • Synonym(s) N-Boc-3-aminobicyclo[1.1.1]pentane-1-carboxylic acid
  • SMILES OC(C1(C2)CC2(NC(OC(C)(C)C)=O)C1)=O

Computational Chemistry Data

  • TPSA   75.63
  • LogP   1.5184
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P260-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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