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Structure of 30486-73-8
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5-Fluoro-1H-benzo[d]imidazol-2-amine features a fluorinated benzimidazole core with a primary amine at the 2-position, offering enhanced electron density and metabolic stability. This scaffold integrates readily into bioactive molecules, serving as a key building block in medicinal chemistry for targeted kinase inhibitors and CNS-active compounds.
5-Fluoro-1H-benzo[d]imidazol-2-amine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to bioactive scaffolds. Its fluorinated aromatic core and amine functionality provide excellent reactivity in Suzuki-Miyaura couplings, Buchwald-Hartwig aminations, and electrophilic substitutions. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis workflows and API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: