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CS-W001157 4
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Methyl 5-{[(tert-butoxy)carbonyl]amino}-2-fluoropyridine-4-carboxylate

  • CAS No. 305371-15-7

  • Cat. No. CS-0049016
  • Molecule weight270.26
  • Purity95+%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl 5-{[(tert-butoxy)carbonyl]amino}-2-fluoropyridine-4-carboxylate|CS-0049016

Structure of 305371-15-7

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General Information

  • CAS No. 305371-15-7
  • Cat. No. CS-0049016
  • Purity 95+%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₅FN₂O₄
  • Molecular Weight 270.26
  • Synonym(s) Methyl 5-(boc-amino)-2-fluoropyridine-4-carboxylate
  • SMILES COC(=O)C1=CC(F)=NC=C1NC(=O)OC(C)(C)C

Synthesis

  • Route1
    • In-stock
      5-((tert-Butoxycarbonyl)amino)-2-fluoroisonicotinic acid|CS-0083017
      171178-42-0
    • null|null
      18107-18-1
    • ~72%
    • Methyl 5-{[(tert-butoxy)carbonyl]amino}-2-fluoropyridine-4-carboxylate|CS-0049016
      305371-15-7

    References

    • American Cyanamid Company Patent: US6355636 B1, 2002 ; Location in patent: Page column 65 ; US 6355636 B1
  • Route2

    References

    • Wissner, Allan; Hamann, Philip R.; Nilakantan, Ramaswamy; Greenberger, Lee M.; Ye, Fei; Rapuano, Timothy A.; Loganzo, Frank Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 6 p. 1411 - 1416
  • Route3

    References

    • Wissner, Allan; Hamann, Philip R.; Nilakantan, Ramaswamy; Greenberger, Lee M.; Ye, Fei; Rapuano, Timothy A.; Loganzo, Frank Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 6 p. 1411 - 1416

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   77.52
  • LogP   2.3543
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   2

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