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CS-W001157 4
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Ethyl 4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate

  • CAS No. 30720-25-3

  • Cat. No. CS-0049469
  • Molecule weight253.68
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Ethyl 4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate|CS-0049469

Structure of 30720-25-3

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General Information

  • CAS No. 30720-25-3
  • Cat. No. CS-0049469
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₂ClN₃O₂
  • Molecular Weight 253.68
  • Synonym(s) ETHYL-4-CHLORO-1-ETHYL-1H-PYRAZOLE [3,4]PYRIDINE-5-CARBOXYLATE
  • SMILES CCOC(=O)C1=CN=C2N(CC)N=CC2=C1Cl

Synthesis

  • Route1
    • null|null
      26823-99-4
    • ~69%
    • Ethyl 4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate|CS-0049469
      30720-25-3

    References

    • RANBAXY LABORATORIES LIMITED Patent: WO2008/111010 A1, 2008 ; Location in patent: Page/Page column 77 ; WO 2008/111010 A1
  • Route2
    • Ethyl 1-ethyl-4-hydroxy-1H-pyrazolo[3,4-b]pyridine-5-carboxylate|CS-1084451
      30720-04-8
    • ~%
    • Ethyl 4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate|CS-0049469
      30720-25-3

    References

    • Bare; McLaren; Campbell; Firor; Resch; Walters; Salama; Meiners; Patel Journal of Medicinal Chemistry, 1989 , vol. 32, # 12 p. 2561 - 2573
  • Route3

    References

    • GLAXO GROUP LIMITED Patent: WO2005/90352 A1, 2005 ; Location in patent: Page/Page column 59-60 ; WO 2005/090352 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   57.01
  • LogP   2.2813
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   3

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