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CS-W001157 4
Total: USD 88.00

2,2'-(p-Tolylazanediyl)diethanol

  • CAS No. 3077-12-1

  • Cat. No. CS-W010620
  • Purity≥98%
  • MDL No.MFCD00020580

*For research and further manufacturing use only, not for direct human use.

2,2'-(p-Tolylazanediyl)diethanol|CS-W010620

Structure of 3077-12-1

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General Information

  • CAS No. 3077-12-1
  • Cat. No. CS-W010620
  • Purity ≥98%
  • MDL No. MFCD00020580
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₇NO₂
  • Molecular Weight 195.26
  • Synonym(s) N,N-Dihydroxyethyl-p-toluidine
  • SMILES CC1=CC=C(N(CCO)CCO)C=C1

Description

2,2-(4-Methylphenylimino)diethanol (p-tolyl diethanolamine) was used as an activating amine.

Application

2,2'-(p-Tolylazanediyl)diethanol serves as a versatile bifunctional scaffold for constructing azo-linked molecular architectures. Its pendant hydroxyl groups enable facile derivatization and purification, while the para-tolyl-azo linkage provides robust stability under standard synthetic conditions. The molecule functions effectively in coupling reactions and serves as a building block for heterocyclic systems and functionalized ligands in medicinal chemistry applications.

Synthesis

  • Route1
    • null|null
      96-49-1
    • null|null
      106-49-0
    • ~9%
    • 2-(P-tolylamino)ethan-1-ol|CS-0318204
      2933-74-6
    • In-stock
      2,2'-(p-Tolylazanediyl)diethanol|CS-W010620
      3077-12-1

    References

    • Synlett, , # 9 p. 1374 - 1378
  • Route2
    • null|null
      75-21-8
    • null|null
      106-49-0
    • ~%
    • In-stock
      2,2'-(p-Tolylazanediyl)diethanol|CS-W010620
      3077-12-1

    References

    • Journal of Organic Chemistry, , vol. 26, p. 1477 - 1480 Journal of the Chemical Society, , p. 183,184
  • Route3
    • null|null
      75-21-8
    • null|null
      106-49-0
    • ~%
    • 2-(P-tolylamino)ethan-1-ol|CS-0318204
      2933-74-6
    • In-stock
      2,2'-(p-Tolylazanediyl)diethanol|CS-W010620
      3077-12-1

    References

    • Justus Liebigs Annalen der Chemie, , vol. 173, p. 117 Justus Liebigs Annalen der Chemie, , vol. 177, p. 49

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H317-H318-H412
Precautionary Statements : P261-P264-P270-P272-P273-P280-P302+P352-P330-P362+P364-P501

Quality Control

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Computational Chemistry Data

  • TPSA   43.7
  • LogP   0.78602
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   5

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