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CS-W001157 4
Total: USD 88.00

Tert-butyl 4-(pyridin-4-yloxy)piperidine-1-carboxylate

  • CAS No. 308386-35-8

  • Cat. No. CS-0450848
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Tert-butyl 4-(pyridin-4-yloxy)piperidine-1-carboxylate|CS-0450848

Structure of 308386-35-8

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General Information

  • CAS No. 308386-35-8
  • Cat. No. CS-0450848
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₂₂N₂O₃
  • Molecular Weight 278.35
  • Synonym(s) 4-(Pyridin-4-yloxy)-piperidine-1-carboxylic acid tert-butyl ester
  • SMILES CC(C)(C)OC(=O)N1CCC(CC1)OC2=CC=NC=C2

Synthesis

  • Route1

    References

    • Takeda Chemical Industries, Ltd. Patent: US6562978 B1, 2003 ;
  • Route2

    References

    • Bailey, James M.; Bruton, Gordon; Huxley, Anthony; Johnstone, Vicky; Milner, Peter H.; Orlek, Barry S.; Stemp, Geoffrey Synlett, 2009 , # 7 p. 1051 - 1054
  • Route3
    • 4-Chloropyridine|CS-0139547
      626-61-9
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      109384-19-2
    • ~%
    • Tert-butyl 4-(pyridin-4-yloxy)piperidine-1-carboxylate|CS-0450848
      308386-35-8

    References

    • GLAXO GROUP LIMITED Patent: WO2005/14571 A1, 2005 ; Location in patent: Page/Page column 16 ; WO 2005/014571 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

Quality Control

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Computational Chemistry Data

  • TPSA   51.66
  • LogP   2.8599
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   2

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