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Structure of 3107-21-9
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1,2,3-Trichloro-5-fluorobenzene features a highly electron-deficient aromatic core stabilized by orthogonal halogen substituents. This configuration enables selective coupling reactions in pharmaceutical synthesis and materials science. The molecule exhibits robust stability under standard reaction conditions, facilitating its use in multi-step transformations requiring precise regiocontrol.
1,2,3-Trichloro-5-fluorobenzene serves as a versatile building block in heterocyclic synthesis and Suzuki-Miyaura coupling reactions. Its orthogonal halogen reactivity enables sequential functionalization, while the fluorine substituent enhances metabolic stability and modulates electronic properties. Bench-stable and compatible with standard cross-coupling conditions, it facilitates efficient access to substituted aryl scaffolds relevant to pharmaceutical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: