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CS-W001157 4
Total: USD 88.00

5-Fluoro-2-pyridinecarbonitrile

  • CAS No. 327056-62-2

  • Cat. No. CS-W009246
  • Purity≥98%
  • MDL No.MFCD08741371
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Fluoro-2-pyridinecarbonitrile|CS-W009246

Structure of 327056-62-2

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Description

5-Fluoro-2-pyridinecarbonitrile serves as a key heterocyclic building block in medicinal chemistry, featuring a fluorinated pyridine core paired with a nitrile group. This combination enables direct incorporation into bioactive scaffolds, leveraging the electron-withdrawing nature of both substituents to modulate reactivity and binding affinity. The compound exhibits bench-stable handling characteristics and compatibility with standard synthetic protocols.

Application

5-Fluoro-2-pyridinecarbonitrile serves as a versatile building block in medicinal chemistry, enabling efficient access to fluorinated pyridine scaffolds via cross-coupling and nucleophilic substitution reactions. Its dual functionality—fluorine at the C5 position and nitrile at C2—provides orthogonal reactivity for downstream derivatization. The compound exhibits excellent bench stability and compatibility with standard synthetic protocols, facilitating purification and integration into complex molecular architectures.

General Information

  • CAS No. 327056-62-2
  • Cat. No. CS-W009246
  • Purity ≥98%
  • MDL No. MFCD08741371
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃FN₂
  • Molecular Weight 122.10
  • Synonym(s) None
  • SMILES N#CC1=NC=C(F)C=C1

Computational Chemistry Data

  • TPSA   36.68
  • LogP   1.09238
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07,GHS09
Signal Word : Danger
UN#: 3439
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H302-H318-H410
Precautionary Statements : P264-P270-P273-P280-P330-P391-P501

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