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Structure of 31181-89-2
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5-Chloro-2-formylpyridine features a strategically positioned formyl group flanked by a chlorine substituent, enabling direct incorporation into heterocyclic scaffolds. This electron-deficient pyridine derivative delivers high reactivity in nucleophilic addition and condensation reactions, particularly valuable in medicinal chemistry and catalyst design.
5-Chloro-2-formylpyridine serves as a versatile building block in medicinal chemistry, enabling efficient access to functionalized heterocycles via electrophilic substitution, nucleophilic addition, and transition-metal-catalyzed coupling reactions. The ortho-formyl group facilitates directed metalation and cyclization, while the chloropyridine moiety supports palladium-mediated cross-coupling. Bench-stable and readily purified by distillation, it functions effectively in multi-step syntheses of kinase inhibitors and other bioactive scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: