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Structure of 31253-08-4
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Ethyl 2-iodopropionate is a reactive alkylating agent featuring a labile iodide moiety flanked by an ester group and a methyl-substituted alpha carbon. This combination enables efficient C–C bond formation in transition-metal-catalyzed cross-coupling reactions, particularly in Negishi and Stille-type processes. The steric profile of the propionate side chain enhances selectivity in complex molecule synthesis, while the ethyl ester provides solubility and stability under standard bench conditions.
Ethyl 2-iodopropionate serves as a versatile alkylating agent in synthetic organic chemistry, enabling efficient introduction of the iodoalkyl motif into target molecules. Its stability under standard bench conditions and compatibility with palladium-catalyzed cross-coupling reactions make it particularly valuable for constructing complex intermediates. The molecule functions effectively in C–C and C–heteroatom bond formation, offering reliable access to functionalized building blocks for medicinal chemistry and materials synthesis.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H227-H315-H319
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Precautionary Statements : P210-P264-P280-P302+P352-P362+P364-P370+P378-P403-P501
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Lot numbers can be found on the outside label of a product: