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Structure of 7425-55-0
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Ethyl 2-iodo-2-methylpropanoate features a sterically hindered α-iodo ester core that enables direct C–C bond formation via Negishi or Stille coupling protocols. This bench-stable reagent integrates readily into complex molecule assembly, offering high functional group tolerance and predictable regiochemistry in palladium-catalyzed transformations.
Ethyl 2-iodo-2-methylpropanoate serves as a robust alkylating agent in synthetic organic chemistry, enabling efficient C–C bond formation via nucleophilic substitution. Its tertiary iodide functionality exhibits high reactivity under mild conditions while maintaining bench stability and ease of purification. The molecule functions effectively in the synthesis of quaternary carbon centers and serves as a key building block for heterocyclic scaffolds and complex molecular architectures in medicinal chemistry workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H227-H315-H319
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Precautionary Statements : P210-P264-P280-P302+P352-P362+P364-P370+P378-P403-P501
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Lot numbers can be found on the outside label of a product: