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CS-W001157 4
Total: USD 88.00

Ethyl 2-Iodopropionate

  • CAS No. 31253-08-4

  • Cat. No. CS-0187740
  • Purity97% GC
  • MDL No.None
  • HazMat Fee +

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    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

Ethyl 2-Iodopropionate|CS-0187740

Structure of 31253-08-4

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Description

Ethyl 2-iodopropionate is a reactive alkylating agent featuring a labile iodide moiety flanked by an ester group and a methyl-substituted alpha carbon. This combination enables efficient C–C bond formation in transition-metal-catalyzed cross-coupling reactions, particularly in Negishi and Stille-type processes. The steric profile of the propionate side chain enhances selectivity in complex molecule synthesis, while the ethyl ester provides solubility and stability under standard bench conditions.

Application

Ethyl 2-iodopropionate serves as a versatile alkylating agent in synthetic organic chemistry, enabling efficient introduction of the iodoalkyl motif into target molecules. Its stability under standard bench conditions and compatibility with palladium-catalyzed cross-coupling reactions make it particularly valuable for constructing complex intermediates. The molecule functions effectively in C–C and C–heteroatom bond formation, offering reliable access to functionalized building blocks for medicinal chemistry and materials synthesis.

General Information

  • CAS No. 31253-08-4
  • Cat. No. CS-0187740
  • Purity 97% GC
  • MDL No. None
  • Storage -20°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₉IO₂
  • Molecular Weight 228.03
  • Synonym(s) 2-Iodopropionic Acid Ethyl Ester
  • SMILES CC(I)C(OCC)=O

Computational Chemistry Data

  • TPSA   26.3
  • LogP   1.373
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H227-H315-H319
Precautionary Statements : P210-P264-P280-P302+P352-P362+P364-P370+P378-P403-P501

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