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CS-W001157 4
Total: USD 88.00

1-[(4-Methylphenyl)sulfonyl]-1H-indole

  • CAS No. 31271-90-6

  • Cat. No. CS-0196101
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1-[(4-Methylphenyl)sulfonyl]-1H-indole|CS-0196101

Structure of 31271-90-6

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General Information

  • CAS No. 31271-90-6
  • Cat. No. CS-0196101
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₃NO₂S
  • Molecular Weight 271.33
  • Synonym(s) N-Tosylindole
  • SMILES CC1=CC=C(C=C1)S(=O)(=O)N2C=CC3=CC=CC=C32

Description

Azido-PEG24-acid is a long chain, monodisperse PEG linker. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Synthesis

  • Route1
    • Indole, ≥99%|CS-1268948
      120-72-9
    • null|null
      98-59-9
    • ~99%
    • In-stock
      1-[(4-Methylphenyl)sulfonyl]-1H-indole|CS-0196101
      31271-90-6

    References

    • Wang, Ke; Liu, Zhanzhu Synthetic Communications, 2010 , vol. 40, # 1 p. 144 - 150
  • Route2
    • null|null
      497066-41-8
    • ~94%
    • In-stock
      1-[(4-Methylphenyl)sulfonyl]-1H-indole|CS-0196101
      31271-90-6

    References

    • Arisawa, Mitsuhiro; Terada, Yukiyoshi; Nakagawa, Masako; Nishida, Atsushi Angewandte Chemie - International Edition, 2002 , vol. 41, # 24 p. 4732 - 4734
  • Route3
    • 1-Tosyl-1H-indole-3-carbonitrile|CS-1635453
      859205-33-7
    • ~82%
    • In-stock
      1-[(4-Methylphenyl)sulfonyl]-1H-indole|CS-0196101
      31271-90-6

    References

    • Tobisu, Mamoru; Nakamura, Ryo; Kita, Yusuke; Chatani, Naoto Bulletin of the Korean Chemical Society, 2010 , vol. 31, # 3 p. 582 - 587

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   39.07
  • LogP   3.18672
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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