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Structure of 313337-34-7
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4-Fluoro-1H-indole-7-carboxylic acid features a fluorinated indole core with a carboxylic acid group at the C7 position, enabling direct incorporation into bioactive molecule scaffolds. The electron-withdrawing fluorine substituent enhances metabolic stability and modulates electronic properties for medicinal chemistry applications. This bench-stable derivative serves as a key building block in the synthesis of targeted therapeutics and functional materials.
4-Fluoro-1H-indole-7-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling direct incorporation of a fluorinated indole scaffold into bioactive molecules. The carboxylic acid group facilitates amide bond formation and derivatization under standard coupling conditions, while the 4-fluoro substitution enhances metabolic stability and modulates electronic properties. Bench-stable and readily purified by recrystallization, it functions reliably in peptide coupling, heterocycle synthesis, and conjugation workflows for API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: