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Structure of 313545-41-4
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4-Chloro-2-(trifluoromethyl)phenylboronic acid features a trifluoromethyl group that enhances electron deficiency and metabolic stability, while the chloro substituent enables downstream functionalization via cross-coupling. This bench-stable boronic acid integrates efficiently into Suzuki-Miyaura reactions, delivering arylated products with high fidelity under standard conditions.
4-Chloro-2-(trifluoromethyl)phenylboronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation with aryl and vinyl halides. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the boronic acid functionality offers excellent bench stability and compatibility with diverse reaction conditions. Its orthogonal reactivity profile facilitates late-stage functionalization in complex molecule synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H319
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: