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Structure of 314020-70-7
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(R)-Bn-Phox is a bench-stable chiral ligand featuring a benzyl-protected phosphine oxide moiety, designed for asymmetric catalysis. The rigid (R)-configuration enables high enantioselectivity in transition metal-catalyzed transformations, particularly in palladium- and rhodium-mediated cross-couplings. This derivative integrates seamlessly into synthetic workflows requiring stereocontrol with minimal handling complexity.
(R)-Bn-Phox serves as a chiral auxiliary in asymmetric synthesis, enabling stereoselective transformations through well-established enolate chemistry. Its benzyl-protected oxazoline framework provides bench stability, excellent functional group tolerance, and facilitates efficient purification. This reagent functions reliably in standard alkylation and conjugate addition protocols, offering predictable stereocontrol for the construction of complex chiral building blocks.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: