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CS-W001157 4
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Ethyl carbamimidate hydrochloride

  • CAS No. 31407-74-6

  • Cat. No. CS-W019160
  • Purity≥95%
  • MDL No.MFCD07438010

*For research and further manufacturing use only, not for direct human use.

Ethyl carbamimidate hydrochloride|CS-W019160

Structure of 31407-74-6

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General Information

  • CAS No. 31407-74-6
  • Cat. No. CS-W019160
  • Purity ≥95%
  • MDL No. MFCD07438010
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₉ClN₂O
  • Molecular Weight 124.57
  • Synonym(s) O-Ethylisourea hydrochloride
  • SMILES N=C(N)OCC.Cl

Description

Ethyl carbamimidate hydrochloride serves as a stable, moisture-tolerant reagent for amidine synthesis. This bench-stable derivative facilitates efficient coupling reactions in peptide modification and heterocyclic chemistry, offering high reactivity with nucleophiles under mild conditions.

Application

Ethyl carbamimidate hydrochloride serves as a reliable reagent for the synthesis of imidazoles and other nitrogen-containing heterocycles, enabling efficient cyclization under mild conditions. Its well-defined reactivity facilitates the formation of C–N bonds with high functional group tolerance, making it valuable in medicinal chemistry scaffolds. The salt form enhances bench stability and simplifies handling, while purification is streamlined due to favorable solubility characteristics in common organic solvents.

Synthesis

  • Route1
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      64-17-5
    • In-stock
      Cyanamide|CS-0008351
      420-04-2
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      23918-45-8
    • ~%
    • In-stock
      Ethyl carbamimidate hydrochloride|CS-W019160
      31407-74-6

    References

    • Journal of the American Chemical Society, , vol. 63, p. 301
  • Route2
    • null|null
      64-17-5
    • In-stock
      Cyanamide|CS-0008351
      420-04-2
    • ~%
    • In-stock
      Ethyl carbamimidate hydrochloride|CS-W019160
      31407-74-6

    References

    • American Chemical Journal, , vol. 26, p. 250

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   59.1
  • LogP   0.33817
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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