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Structure of 31462-58-5
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5-Iodopyrimidine features a reactive iodine atom at the 5-position, enabling efficient cross-coupling transformations. This bench-stable heterocycle integrates readily into pharmaceutical intermediates and functional materials, offering high regioselectivity in Pd-catalyzed reactions.
5-Iodopyrimidine serves as a versatile building block in cross-coupling chemistry, enabling efficient C–C and C–heteroatom bond formation under palladium catalysis. Its iodine substituent provides high reactivity in Suzuki, Stille, and Negishi couplings, facilitating the construction of substituted pyrimidines with excellent functional group tolerance. The molecule exhibits good bench stability and is readily purified by distillation or recrystallization, making it well-suited for use in medicinal chemistry and materials synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: