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Structure of 315-31-1
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2-Fluoro-3-methylbenzoic acid features a strategically positioned fluorine atom and methyl group on the aromatic ring, enhancing electronic effects and metabolic stability. This ortho-substituted benzoic acid derivative serves as a key building block in medicinal chemistry, particularly for designing bioactive molecules requiring precise steric and electronic tuning.
2-Fluoro-3-methylbenzoic acid serves as a valuable building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-fluoro and meta-methyl substituents provide enhanced metabolic stability and modulate electronic properties, facilitating coupling reactions with amines, alcohols, and nucleophiles under standard conditions. The carboxylic acid group offers direct functionality for amide formation, esterification, or salt formation, while the molecule exhibits good bench stability and ease of purification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: