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Structure of 185147-07-3
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2-Fluoro-3-methylbenzonitrile features a fluorinated aromatic ring with adjacent methyl and nitrile groups, offering enhanced electron-withdrawing character and improved metabolic stability. This configuration enables efficient incorporation into pharmaceutical intermediates and advanced materials, particularly in the synthesis of kinase inhibitors and functionalized polymers under standard reaction conditions.
2-Fluoro-3-methylbenzonitrile serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the electron-deficient aromatic ring. Its fluorine and nitrile groups offer orthogonal reactivity for late-stage derivatization, while the methyl substituent provides a handle for oxidation or cross-coupling. Bench-stable and compatible with standard coupling protocols, it facilitates efficient access to substituted benzimidazoles, pyridines, and other heterocyclic scaffolds relevant to API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: