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Structure of 3177-20-6
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Methyl 2,4-dichloropyrimidine-5-carboxylate features a pyrimidine core with strategically positioned chloro and ester groups, enabling direct functionalization in medicinal chemistry. The electron-deficient ring facilitates nucleophilic substitution, while the methyl ester serves as a handle for downstream derivatization. This compound delivers high reactivity under mild conditions, streamlining access to advanced heterocyclic scaffolds.
Methyl 2,4-dichloropyrimidine-5-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling efficient access to substituted pyrimidines via nucleophilic displacement. The dichloro substitution pattern facilitates sequential functionalization at C2 and C4, while the ester group allows for further derivatization or hydrolysis. Its bench-stable nature and compatibility with diverse reaction conditions make it a practical choice for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: