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Structure of 317810-73-4
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6-(Difluoromethoxy)pyridin-3-amine features a difluoromethoxy group at the 6-position and a primary amine at the 3-position of a pyridine ring, creating a polar, electron-deficient heteroaromatic scaffold. This configuration enhances solubility in organic solvents while maintaining stability under standard bench conditions. The molecule integrates readily into pharmaceutical intermediates, serving as a key building block for kinase inhibitors and other bioactive compounds where fluorinated ether linkages improve metabolic resistance and membrane permeability.
6-(Difluoromethoxy)pyridin-3-amine serves as a versatile building block in medicinal chemistry, enabling efficient access to bioactive heterocycles. Its difluoromethoxy group enhances metabolic stability and modulates lipophilicity, while the primary amine facilitates direct coupling reactions. The molecule exhibits excellent bench stability and compatibility with standard functional group transformations, making it ideal for parallel synthesis and scaffold diversification in API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: